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U2AF2 抗体 (AA 124-246)

This anti-U2AF2 antibody is a 兔 多克隆 antibody detecting U2AF2 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7170633
发货至: 中国
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Quick Overview for U2AF2 抗体 (AA 124-246) (ABIN7170633)

抗原

See all U2AF2 (U2AF59) 抗体
U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))

适用

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宿主

  • 58
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克隆类型

  • 46
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多克隆

标记

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This U2AF2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

    • 9
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    AA 124-246

    原理

    U2AF2 Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Splicing factor U2AF 65 kDa subunit protein (124-246AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))

    别名

    U2AF2

    背景

    Background: Necessary for the splicing of pre-mRNA. By recruiting PRPF19 and the PRP19C/Prp19 complex/NTC/Nineteen complex to the RNA polymerase II C-terminal domain (CTD), and thereby pre-mRNA, may couple transcription to splicing (PubMed:21536736). Induces cardiac troponin-T (TNNT2) pre-mRNA exon inclusion in muscle. Regulates the TNNT2 exon 5 inclusion through competition with MBNL1. Binds preferentially to a single-stranded structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron-less gene. Represses the splicing of MAPT/Tau exon 10.

    Aliases: hU2AF(65) antibody, hU2AF65 antibody, Splicing factor U2AF 65 kDa subunit antibody, U2 (RNU2) small nuclear RNA auxiliary factor 2 antibody, U2 auxiliary factor 65 kDa subunit antibody, U2 small nuclear ribonucleoprotein auxiliary factor (65kD) antibody, U2 small nuclear RNA auxiliary factor 2 antibody, U2 snRNP auxiliary factor large subunit antibody, U2af2 antibody, U2AF2_HUMAN antibody, U2AF65 antibody

    UniProt

    P26368
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