SKA3 抗体 (AA 101-195)
Quick Overview for SKA3 抗体 (AA 101-195) (ABIN7170595)
抗原
See all SKA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-195
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Spindle and kinetochore-associated protein 3 protein (101-195AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SKA3 (Spindle and Kinetochore Associated Complex Subunit 3 (SKA3))
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别名
- SKA3
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背景
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Background: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:19289083, PubMed:19360002, PubMed:23085020). The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083, PubMed:19360002). The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner (PubMed:19289083). In the complex, it mediates the microtubule-stimulated oligomerization (PubMed:19289083). Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020).
Aliases: C13orf3 antibody, RAMA1 antibody, SKA3 antibody, SKA3_HUMAN antibody, Spindle and kinetochore associated complex subunit 3 antibody, Spindle and kinetochore-associated protein 3 antibody
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UniProt
- Q8IX90
抗原
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