SKA1 抗体 (AA 61-134)
Quick Overview for SKA1 抗体 (AA 61-134) (ABIN7170587)
抗原
See all SKA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 61-134
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Spindle and kinetochore-associated protein 1 protein (61-134AA)
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亚型
- IgG
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anti-Spindle and Kinetochore Associated Complex Subunit 1 (SKA1) (C-Term) antibody
SKA1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Spindle and Kinetochore Associated Complex Subunit 1 (SKA1) (AA 51-100) antibodySKA1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:200-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SKA1 (Spindle and Kinetochore Associated Complex Subunit 1 (SKA1))
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别名
- SKA1
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背景
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Background: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:17093495, PubMed:19289083, PubMed:23085020). Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint (PubMed:17093495). The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083). The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner (PubMed:19289083). Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020). In the complex, it mediates the interaction with microtubules (PubMed:19289083, PubMed:23085020).
Aliases: 2810433K01Rik antibody, AV117428 antibody, C18orf24 antibody, MGC10200 antibody, Ska1 antibody, SKA1_HUMAN antibody, Spindle and kinetochore associated complex subunit 1 antibody, Spindle and kinetochore associated protein 1 antibody, Spindle and kinetochore-associated protein 1 antibody, Spindle and KT (kinetochore) associated 1 antibody, Spindle and KT associated 1 antibody
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UniProt
- Q96BD8
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途径
- M Phase
抗原
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