SPAG5 抗体 (AA 1-300)
Quick Overview for SPAG5 抗体 (AA 1-300) (ABIN7170478)
抗原
See all SPAG5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-300
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Sperm-associated antigen 5 protein (1-300AA)
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亚型
- IgG
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anti-Sperm Associated Antigen 5 (SPAG5) (AA 1101-1193) antibody
SPAG5 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 5 (SPAG5) (AA 1082-1191) antibodySPAG5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5F9 unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SPAG5 (Sperm Associated Antigen 5 (SPAG5))
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别名
- SPAG5
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背景
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Background: Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. In complex with SKAP, promotes stable microtubule-kinetochore attachments. May contribute to the regulation of separase activity. May regulate AURKA localization to mitotic spindle, but not to centrosomes and CCNB1 localization to both mitotic spindle and centrosomes. In non-mitotic cells, upon stress induction, inhibits mammalian target of rapamycin complex 1 (mTORC1) association and recruits the mTORC1 component RPTOR to stress granules (SGs), thereby preventing mTORC1 hyperactivation-induced apoptosis. May enhance GSK3B-mediated phosphorylation of other substrates, such as MAPT/TAU.
Aliases: Astrin antibody, Deepest antibody, hMAP 126 antibody, hMAP126 antibody, MAP 126 antibody, MAP126 antibody, Mitotic spindle associated protein antibody, Mitotic spindle associated protein p126 antibody, Mitotic spindle coiled coil related protein antibody, Mitotic spindle-associated protein p126 antibody, SPAG 5 antibody, SPAG5 antibody, SPAG5_HUMAN antibody, Sperm associated antigen 5 antibody, Sperm tail protein Spag 5 antibody, Sperm tail protein Spag5 antibody, Sperm-associated antigen 5 antibody
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UniProt
- Q96R06
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途径
- M Phase
抗原
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