SLC38A9 抗体 (AA 1-119)
Quick Overview for SLC38A9 抗体 (AA 1-119) (ABIN7169972)
抗原
See all SLC38A9 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-119
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Sodium-coupled neutral amino acid transporter 9 protein (1-119AA)
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亚型
- IgG
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anti-Solute Carrier Family 38, Member 9 (SLC38A9) (AA 218-267) antibody
SLC38A9 适用: 人, 犬, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SLC38A9 (Solute Carrier Family 38, Member 9 (SLC38A9))
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别名
- SLC38A9
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背景
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Background: Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acids. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids (PubMed:25561175, PubMed:25567906). Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of amino acids with low capacity and specificity with a slight preference for polar amino acids, suggesting that it acts as an amino acid sensor instead (PubMed:25561175, PubMed:25567906). The high concentration of arginine in lysosomes suggests that it acts as an arginine sensor (PubMed:25567906).
Aliases: FLJ46104 antibody, FLJ90709 antibody, Homo sapiens solute carrier family 38, member 9 antibody, MGC120544 antibody, OTTHUMP00000161835 antibody, Putative sodium coupled neutral amino acid transporter 9 antibody, Putative sodium-coupled neutral amino acid transporter 9 antibody, Putative uncharacterized protein FLJ90709 antibody, S38A9_HUMAN antibody, SLC38A9 antibody
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UniProt
- Q8NBW4
抗原
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