SUMO2 抗体 (AA 1-84)
Quick Overview for SUMO2 抗体 (AA 1-84) (ABIN7169885)
抗原
See all SUMO2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-84
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Small ubiquitin-related modifier 2 protein (1-84AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))
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别名
- SUMO2
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背景
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Background: Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2, CBX4 or ZNF451 (PubMed:26524494). This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins (PubMed:18408734, PubMed:18538659, PubMed:21965678, PubMed:9556629). Plays a role in the regulation of sumoylation status of SETX (PubMed:24105744).
Aliases: HSMT 3 antibody, HSMT3 antibody, MGC117191 antibody, Sentrin 2 antibody, Sentrin-2 antibody, Sentrin2 antibody, Small ubiquitin like modifier 2 antibody, Small ubiquitin related modifier 2 antibody, Small ubiquitin-related modifier 2 antibody, SMT 3B antibody, SMT3 homolog 2 antibody, SMT3 suppressor of mif two 3 homolog 2 antibody, SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) antibody, SMT3, yeast, homolog 2 antibody, Smt3A antibody, SMT3B antibody, SMT3H2 antibody, SUMO-2 antibody, SUMO-3 antibody, SUMO2 antibody, SUMO2_HUMAN antibody, Sumo3 antibody, Ubiquitin like protein SMT3B antibody, Ubiquitin-like protein SMT3A antibody
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UniProt
- P61956
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途径
- Methionine Biosynthetic Process
抗原
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