STAM2 抗体 (AA 376-525)
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北京 101111
Quick Overview for STAM2 抗体 (AA 376-525) (ABIN7169694)
抗原
See all STAM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 376-525
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原理
- STAM2 Antibody
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Signal transducing adapter molecule 2 protein (376-525AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))
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别名
- STAM2
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背景
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Background: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).
Aliases: DKFZp564C047 antibody, Hbp antibody, Hrs-binding protein antibody, HSE1 homolog antibody, Signal transducing adapter molecule 2 antibody, Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 antibody, Signal transducing adaptor molecule 2A antibody, Signal transducing adaptor molecule 2B antibody, Signal transducing adaptor molecule antibody, STAM like protein containing SH3 and ITAM domains 2 antibody, STAM-2 antibody, Stam2 antibody, STAM2_HUMAN antibody, STAM2A antibody, STAM2B antibody
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UniProt
- O75886
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途径
- EGFR Signaling Pathway, EGFR Downregulation
抗原
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