SPPL2A 抗体 (AA 26-172) (FITC)
Quick Overview for SPPL2A 抗体 (AA 26-172) (FITC) (ABIN7169625)
抗原
See all SPPL2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 26-172
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Signal peptide peptidase-like 2A protein (26-172AA)
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亚型
- IgG
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anti-Signal Peptide Peptidase-Like 2A (SPPL2A) (AA 26-172) antibody
SPPL2A 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal Peptide Peptidase-Like 2A (SPPL2A) (AA 31-129) antibodySPPL2A 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1C7 unconjugated
anti-Signal Peptide Peptidase-Like 2A (SPPL2A) (AA 421-520) antibodySPPL2A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Signal Peptide Peptidase-Like 2A (SPPL2A) (AA 31-129) antibodySPPL2A 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Signal Peptide Peptidase-Like 2A (SPPL2A) (AA 108-138), (N-Term) antibodySPPL2A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2267 unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SPPL2A (Signal Peptide Peptidase-Like 2A (SPPL2A))
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别名
- SPPL2A
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背景
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Background: Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in FASLG, ITM2B and TNF processing (PubMed:16829952, PubMed:16829951, PubMed:17557115, PubMed:17965014). Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF-alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus (PubMed:16829952). Also responsible for the intramembrane cleavage of Fas antigen ligand FASLG, which promotes the release of the intracellular FasL domain (FasL ICD) (PubMed:17557115). May play a role in the regulation of innate and adaptive immunity (PubMed:16829952). Catalyzes the intramembrane cleavage of the simian foamy virus envelope glycoprotein gp130 independently of prior ectodomain shedding by furin or furin-like proprotein convertase (PC)-mediated cleavage proteolysis (PubMed:23132852).
Aliases: SPPL2A antibody, IMP3 antibody, PSL2 antibody, PSEC0147 antibody, Signal peptide peptidase-like 2A antibody, SPP-like 2A antibody, SPPL2a antibody, EC 3.4.23.- antibody, Intramembrane protease 3 antibody, IMP-3 antibody, Presenilin-like protein 2 antibody
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UniProt
- Q8TCT8
抗原
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