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WNK3 抗体 (AA 1018-1181)

This anti-WNK3 antibody is a 兔 多克隆 antibody detecting WNK3 in ELISA 和 IF. Suitable for 人.
产品编号 ABIN7169230
发货至: 中国

Quick Overview for WNK3 抗体 (AA 1018-1181) (ABIN7169230)

抗原

See all WNK3 抗体
WNK3 (WNK Lysine Deficient Protein Kinase 3 (WNK3))

适用

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宿主

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克隆类型

  • 46
  • 5
多克隆

标记

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This WNK3 antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 8
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    • 1
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    AA 1018-1181

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Serine/threonine-protein kinase WNK3 protein (1018-1181AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    WNK3 (WNK Lysine Deficient Protein Kinase 3 (WNK3))

    别名

    WNK3

    背景

    Background: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively (PubMed:16275913, PubMed:16275911, PubMed:16357011). Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2. Increases Ca(2+) influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway (PubMed:18768590). Inhibits the activity of KCNJ1 by decreasing its expression at the cell membrane in a non-catalytic manner.

    Aliases: KIAA1566 antibody, PRKWNK 3 antibody, PRKWNK3 antibody, Protein kinase lysine deficient 3 antibody, Protein kinase lysine-deficient 3 antibody, Protein kinase with no lysine 3 antibody, Serine/threonine protein kinase WNK3 antibody, Serine/threonine-protein kinase WNK3 antibody, WNK 3 antibody, WNK lysine deficient protein kinase 3 antibody, Wnk3 antibody, WNK3_HUMAN antibody

    UniProt

    Q9BYP7
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