NEK2 抗体 (AA 1-135)
Quick Overview for NEK2 抗体 (AA 1-135) (ABIN7169100)
抗原
See all NEK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-135
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Serine/threonine-protein kinase Nek2 protein (1-135AA)
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亚型
- IgG
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anti-NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2) (AA 148-397) antibody
NEK2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2) (AA 331-445) antibodyNEK2 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 2F6 unconjugated
anti-NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2) (AA 331-445) antibodyNEK2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2) (AA 1-445) antibodyNEK2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2) (AA 1-445) antibodyNEK2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2) (AA 282-295) antibodyNEK2 适用: 人 WB 宿主: 绵羊 Monoclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2) (AA 331-445) antibodyNEK2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C8 unconjugated
anti-NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2) (C-Term) antibodyNEK2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2) (AA 125-393) antibodyNEK2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2) (AA 396-426) antibodyNEK2 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- NEK2 (NIMA (Never in Mitosis Gene A)-Related Kinase 2 (NEK2))
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别名
- NEK2
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背景
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Background: Protein kinase which is involved in the control of centrosome separation and bipolar spindle formation in mitotic cells and chromatin condensation in meiotic cells. Regulates centrosome separation (essential for the formation of bipolar spindles and high-fidelity chromosome separation) by phosphorylating centrosomal proteins such as CROCC, CEP250 and NINL, resulting in their displacement from the centrosomes. Regulates kinetochore microtubule attachment stability in mitosis via phosphorylation of NDC80. Involved in regulation of mitotic checkpoint protein complex via phosphorylation of CDC20 and MAD2L1. Plays an active role in chromatin condensation during the first meiotic division through phosphorylation of HMGA2. Phosphorylates: PPP1CC, SGOL1, NECAB3 and NPM1. Essential for localization of MAD2L1 to kinetochore and MAPK1 and NPM1 to the centrosome. Isoform 1 phosphorylates and activates NEK11 in G1/S-arrested cells. Isoform 2, which is not present in the nucleolus, does not.
Aliases: HSPK 21 antibody, HsPK21 antibody, NEK 2 antibody, NEK2 antibody, NEK2_HUMAN antibody, NEK2A antibody, Never in mitosis A-related kinase 2 antibody, NIMA (never in mitosis gene a) related kinase 2 antibody, NimA like protein kinase 1 antibody, NIMA related kinase 2 antibody, NimA related protein kinase 2 antibody, NimA-like protein kinase 1 antibody, NimA-related protein kinase 2 antibody, NLK 1 antibody, NLK1 antibody, Serine/threonine-protein kinase Nek2 antibody
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UniProt
- P51955
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途径
- M Phase
抗原
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