PKN2 抗体 (AA 925-969)
Quick Overview for PKN2 抗体 (AA 925-969) (ABIN7169080)
抗原
See all PKN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 925-969
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Serine/threonine-protein kinase N2 protein (925-969AA)
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亚型
- IgG
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anti-Protein Kinase N2 (PKN2) antibody
PKN2 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1D1 unconjugated
anti-Protein Kinase N2 (PKN2) (AA 580-679) antibodyPKN2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A7 unconjugated
anti-Protein Kinase N2 (PKN2) antibodyPKN2 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase N2 (PKN2) (AA 67-312) antibodyPKN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase N2 (PKN2) (AA 108-141) antibodyPKN2 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB50147 unconjugated
anti-Protein Kinase N2 (PKN2) (AA 891-940) antibodyPKN2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase N2 (PKN2) (AA 605-654) antibodyPKN2 适用: 人, Cow, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase N2 (PKN2) antibodyPKN2 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Protein Kinase N2 (PKN2) (C-Term) antibodyPKN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase N2 (PKN2) (AA 323-464) antibodyPKN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PKN2 (Protein Kinase N2 (PKN2))
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别名
- PKN2
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背景
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Background: PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion and transcription activation signaling processes. Phosphorylates CTTN in hyaluronan-induced astrocytes and hence decreases CTTN ability to associate with filamentous actin. Phosphorylates HDAC5, therefore lead to impair HDAC5 import. Direct RhoA target required for the regulation of the maturation of primordial junctions into apical junction formation in bronchial epithelial cells. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Stimulates FYN kinase activity that is required for establishment of skin cell-cell adhesion during keratinocytes differentiation. Regulates epithelial bladder cells speed and direction of movement during cell migration and tumor cell invasion. Inhibits Akt pro-survival-induced kinase activity. Mediates Rho protein-induced transcriptional activation via the c-fos serum response factor (SRF). Phosphorylates HCV NS5B leading to stimulation of HCV RNA replication.
Aliases: Cardiolipin activated protein kinase Pak2 antibody, MGC150606 antibody, MGC71074 antibody, PAK 2 antibody, PAK2 antibody, PKN gamma antibody, PKN2 antibody, PKN2_HUMAN antibody, PRK2 antibody, PRKCL2 antibody, PRO2042 antibody, Protein kinase C like 2 antibody, Protein kinase C related kinase 2 antibody, Protein kinase C-like 2 antibody, Protein kinase N2 antibody, Protein-kinase C-related kinase 2 antibody, Serine/threonine-protein kinase N2 antibody
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UniProt
- Q16513
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途径
- Cell-Cell Junction Organization
抗原
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