ICK 抗体 (AA 150-275)
Quick Overview for ICK 抗体 (AA 150-275) (ABIN7169051)
抗原
See all ICK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 150-275
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Serine/threonine-protein kinase ICK protein (150-275AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ICK (Intestinal Cell (MAK-Like) Kinase (ICK))
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别名
- ICK
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背景
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Background: Required for ciliogenesis (PubMed:24797473). Phosphorylates KIF3A (By similarity). Involved in the control of ciliary length (PubMed:24853502). Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity). May play a key role in the development of multiple organ systems and particularly in cardiac development (By similarity). Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner and this regulation requires its kinase activity (By similarity).
Aliases: CILK1 antibody, ICK antibody, KIAA0936Serine/threonine-protein kinase ICK antibody, EC 2.7.11.1 antibody, Ciliogenesis associated kinase 1 antibody, Intestinal cell kinase antibody, hICK antibody, Laryngeal cancer kinase 2 antibody, LCK2 antibody, MAK-related kinase antibody, MRK antibody
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UniProt
- Q9UPZ9
抗原
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