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SRSF1 抗体 (AA 1-248)

This anti-SRSF1 antibody is a 兔 多克隆 antibody detecting SRSF1 in IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7168966
发货至: 中国

Quick Overview for SRSF1 抗体 (AA 1-248) (ABIN7168966)

抗原

See all SRSF1 抗体
SRSF1 (serine/arginine-Rich Splicing Factor 1 (SRSF1))

适用

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宿主

  • 52
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克隆类型

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  • 12
多克隆

标记

  • 33
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This SRSF1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 1-248

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Serine/arginine-rich splicing factor 1 protein (1-248AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    SRSF1 (serine/arginine-Rich Splicing Factor 1 (SRSF1))

    别名

    SRSF1

    背景

    Background: Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5\\\'- and 3\\\'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5\\\'-splice site-containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5\\\'-RGAAGAAC-3\\\' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5\\\'-CGAGGCG-3\\\' motif in vitro. Three copies of the octamer constitute a powerful splicing enhancer in vitro, the ASF/SF2 splicing enhancer (ASE) which can specifically activate ASE-dependent splicing. Isoform ASF-2 and isoform ASF-3 act as splicing repressors. May function as export adapter involved in mRNA nuclear export through the TAP/NXF1 pathway.

    Aliases: Alternative splicing factor 1 antibody, Alternative-splicing factor 1 antibody, arginine/serine-rich 1 antibody, ASF 1 antibody, ASF antibody, ASF-1 antibody, ASF1 antibody, FLJ53078 antibody, MGC5228 antibody, P33 subunit antibody, Pre mRNA splicing factor SF2 P33 subunit antibody, pre-mRNA-splicing factor SF2 antibody, Serine/arginine-rich splicing factor 1 antibody, SF2 antibody, SF2P33 antibody, SFRS1 antibody, Splicing factor 2 alternate splicing factor antibody, Splicing factor 2 antibody, Splicing factor antibody, Splicing factor arginine/serine rich 1 antibody, SR Splicing factor 1 antibody, SRp30a antibody, srsf1 antibody, SRSF1_HUMAN antibody

    UniProt

    Q07955

    途径

    Ribonucleoprotein Complex Subunit Organization
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