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SENP6 抗体 (AA 1-270)

This anti-SENP6 antibody is a 兔 多克隆 antibody detecting SENP6 in ELISA 和 IF. Suitable for 人.
产品编号 ABIN7168841
发货至: 中国

Quick Overview for SENP6 抗体 (AA 1-270) (ABIN7168841)

抗原

See all SENP6 抗体
SENP6 (SUMO1/sentrin Specific Protease 6 (SENP6))

适用

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宿主

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克隆类型

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多克隆

标记

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This SENP6 antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 1-270

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Sentrin-specific protease 6 protein (1-270AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    SENP6 (SUMO1/sentrin Specific Protease 6 (SENP6))

    别名

    SENP6

    背景

    Background: Protease that deconjugates SUMO1, SUMO2 and SUMO3 from targeted proteins. Processes preferentially poly-SUMO2 and poly-SUMO3 chains, but does not efficiently process SUMO1, SUMO2 and SUMO3 precursors. Deconjugates SUMO1 from RXRA, leading to transcriptional activation. Involved in chromosome alignment and spindle assembly, by regulating the kinetochore CENPH-CENPI-CENPK complex. Desumoylates PML and CENPI, protecting them from degradation by the ubiquitin ligase RNF4, which targets polysumoylated proteins for proteasomal degradation. Desumoylates also RPA1, thus preventing recruitment of RAD51 to the DNA damage foci to initiate DNA repair through homologous recombination.

    Aliases: 2810017C20Rik antibody, FLJ11355 antibody, FLJ11887 antibody, KIAA0389 antibody, KIAA0797 antibody, SENP 6 antibody, Senp6 antibody, SENP6_HUMAN antibody, Sentrin specific protease 6 antibody, Sentrin-specific protease 6 antibody, Sentrin/SUMO specific protease SENP6 antibody, Sentrin/SUMO-specific protease SENP6 antibody, SSP 1 antibody, SSP1 antibody, SUMO 1 specific protease 1 antibody, SUMO 1 specific protease antibody, SUMO-1-specific protease 1 antibody, SUMO1 specific protease 1 antibody, SUMO1 specific protease antibody, SUMO1/sentrin specific peptidase 6 antibody, SUSP 1 antibody, SUSP1 antibody

    UniProt

    Q9GZR1
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