SLFN11 抗体 (AA 670-821)
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北京 101111
Quick Overview for SLFN11 抗体 (AA 670-821) (ABIN7168622)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 670-821
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原理
- SLFN11 Antibody
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交叉反应
- 小鼠
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human Schlafen family member 11 protein (670-821AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SLFN11 (Schlafen Family Member 11 (SLFN11))
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别名
- SLFN11
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背景
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Background: Interferon (IFN)-induced antiviral protein which acts as an inhibitor of retrovirus protein synthesis. Specifically abrogates the production of retroviruses such as human immunodeficiency virus 1 (HIV-1) by acting as a specific inhibitor of the synthesis of retroviruses encoded proteins in a codon-usage-dependent manner. Binds to tRNAs and exploits the unique viral codon bias towards A/T nucleotides. The exact inhibition mechanism is unclear: may either sequesters tRNAs, prevents their maturation via post-transcriptional processing or accelerates their deacylation. Does not inhibit reverse transcription, integration or production and nuclear export of viral RNA. May play a role in cell cycle arrest and/or induction of apoptosis in response to exogenously induced DNA damage.
Aliases: SLFN11 antibody, Schlafen family member 11 antibody, EC 3.6.-.- antibody
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UniProt
- Q7Z7L1
抗原
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