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RBM4 抗体 (AA 121-205) (FITC)

This anti-RBM4 antibody is a 兔 多克隆 antibody detecting RBM4 in . Suitable for 人.
产品编号 ABIN7168347
发货至: 中国

Quick Overview for RBM4 抗体 (AA 121-205) (FITC) (ABIN7168347)

抗原

See all RBM4 抗体
RBM4 (RNA Binding Motif Protein 4 (RBM4))

适用

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宿主

  • 25
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克隆类型

  • 25
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多克隆

标记

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This RBM4 antibody is conjugated to FITC

应用范围

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  • 抗原表位

    • 8
    • 6
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    AA 121-205

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human RNA-binding protein 4 protein (121-205AA)

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    RBM4 (RNA Binding Motif Protein 4 (RBM4))

    别名

    RBM4

    背景

    Background: RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5\\\'-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs. Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3\\\'-UTR of the PER1 mRNA. Exerts a suppressive activity on Cap-dependent translation via binding to CU-rich responsive elements within the 3\\\'UTR of mRNAs, a process increased under stress conditions or during myocytes differentiation. Recruits EIF4A1 to stimulate IRES-dependent translation initiation in respons to cellular stress. Associates to internal ribosome entry segment (IRES) in target mRNA species under stress conditions. Plays a role for miRNA-guided RNA cleavage and translation suppression by promoting association of AGO2-containing miRNPs with their cognate target mRNAs. Associates with miRNAs during muscle cell differentiation. Binds preferentially to 5\\\'-CGCGCG[GCA]-3\\\' motif in vitro.

    Aliases: dkfzp547k0918 antibody, hLark antibody, lark antibody, Lark homolog antibody, lark homologue antibody, mgc75138 antibody, RBM4 antibody, rbm4 lark antibody, RBM4_HUMAN antibody, RNA binding motif 4 antibody, RNA binding motif 4a antibody, RNA-binding motif protein 4 antibody, RNA-binding motif protein 4a antibody, RNA-binding protein 4 antibody

    UniProt

    Q9BWF3

    途径

    Regulation of Muscle Cell Differentiation, Photoperiodism
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