RBM4 抗体 (AA 121-205) (FITC)
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北京 101111
Quick Overview for RBM4 抗体 (AA 121-205) (FITC) (ABIN7168347)
抗原
See all RBM4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 121-205
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原理
- RBM4 Antibody, FITC conjugated
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human RNA-binding protein 4 protein (121-205AA)
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亚型
- IgG
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anti-RNA Binding Motif Protein 4 (RBM4) (Internal Region) antibody
RBM4 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RNA Binding Motif Protein 4 (RBM4) (AA 121-205) antibodyRBM4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RNA Binding Motif Protein 4 (RBM4) antibodyRBM4 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-RNA Binding Motif Protein 4 (RBM4) (AA 152-201) antibodyRBM4 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-RNA Binding Motif Protein 4 (RBM4) (AA 177-207) antibodyRBM4 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-RNA Binding Motif Protein 4 (RBM4) (Middle Region) antibodyRBM4 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, Cow, 犬, 山羊 WB 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RBM4 (RNA Binding Motif Protein 4 (RBM4))
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别名
- RBM4
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背景
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Background: RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5\\\'-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs. Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3\\\'-UTR of the PER1 mRNA. Exerts a suppressive activity on Cap-dependent translation via binding to CU-rich responsive elements within the 3\\\'UTR of mRNAs, a process increased under stress conditions or during myocytes differentiation. Recruits EIF4A1 to stimulate IRES-dependent translation initiation in respons to cellular stress. Associates to internal ribosome entry segment (IRES) in target mRNA species under stress conditions. Plays a role for miRNA-guided RNA cleavage and translation suppression by promoting association of AGO2-containing miRNPs with their cognate target mRNAs. Associates with miRNAs during muscle cell differentiation. Binds preferentially to 5\\\'-CGCGCG[GCA]-3\\\' motif in vitro.
Aliases: dkfzp547k0918 antibody, hLark antibody, lark antibody, Lark homolog antibody, lark homologue antibody, mgc75138 antibody, RBM4 antibody, rbm4 lark antibody, RBM4_HUMAN antibody, RNA binding motif 4 antibody, RNA binding motif 4a antibody, RNA-binding motif protein 4 antibody, RNA-binding motif protein 4a antibody, RNA-binding protein 4 antibody
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UniProt
- Q9BWF3
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途径
- Regulation of Muscle Cell Differentiation, Photoperiodism
抗原
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