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TARBP2 抗体 (AA 1-366)

This anti-TARBP2 antibody is a 兔 多克隆 antibody detecting TARBP2 in IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7168268
发货至: 中国
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Quick Overview for TARBP2 抗体 (AA 1-366) (ABIN7168268)

抗原

See all TARBP2 抗体
TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))

适用

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宿主

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克隆类型

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多克隆

标记

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This TARBP2 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
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    AA 1-366

    原理

    TARBP2 Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human RISC-loading complex subunit TARBP2 protein (1-366AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))

    别名

    TARBP2

    背景

    Background: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1. Binds to the HIV-1 TAR RNA which is located in the long terminal repeat (LTR) of HIV-1, and stimulates translation of TAR-containing RNAs. This is achieved in part at least by binding to and inhibiting EIF2AK2/PKR, thereby reducing phosphorylation and inhibition of EIF2S1/eIF-2-alpha. May also promote translation of TAR-containing RNAs independently of EIF2AK2/PKR.

    Aliases: LOQS antibody, Prbp antibody, RISC loading complex subunit TARBP2 antibody, RISC-loading complex subunit tarbp2 antibody, TAR (HIV 1) RNA binding protein 2 antibody, TAR (HIV) RNA binding protein 2 antibody, TAR (HIV) RNA-binding protein TRBP1 antibody, TAR RNA Binding Protein 2 antibody, TAR RNA-binding protein 2 antibody, tarbp2 antibody, TARBP2 RISC loading complex RNA binding subunit antibody, Trans-activation-responsive RNA-binding protein antibody, TRBP antibody, TRBP1 antibody, TRBP2 antibody, TRBP2_HUMAN antibody

    UniProt

    Q15633

    途径

    Regulatory RNA Pathways, Ribonucleoprotein Complex Subunit Organization
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