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RNF11 抗体 (AA 1-154)

This 兔 多克隆 antibody specifically detects RNF11 in ELISA 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN7168238
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for RNF11 抗体 (AA 1-154) (ABIN7168238)

抗原

See all RNF11 抗体
RNF11 (Ring Finger Protein 11 (RNF11))

适用

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宿主

  • 35
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克隆类型

  • 36
  • 2
多克隆

标记

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This RNF11 antibody is un-conjugated

应用范围

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  • 11
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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-154

    原理

    RNF11 Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human RING finger protein 11 protein (1-154AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    RNF11 (Ring Finger Protein 11 (RNF11))

    别名

    RNF11

    背景

    Background: Essential component of a ubiquitin-editing protein complex, comprising also TNFAIP3, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. Promotes the association of TNFAIP3 to RIPK1 after TNF stimulation. TNFAIP3 deubiquitinates \\\'Lys-63\\\' polyubiquitin chains on RIPK1 and catalyzes the formation of \\\'Lys-48\\\'-polyubiquitin chains. This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NF-kappa-B. Recruits STAMBP to the E3 ubiquitin-ligase SMURF2 for ubiquitination, leading to its degradation by the 26S proteasome.

    Aliases: CGI 123 antibody, RING finger protein 11 antibody, RNF11 antibody, RNF11_HUMAN antibody, Sid 1669 antibody, SID1669 antibody

    UniProt

    Q9Y3C5
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