RHOH 抗体 (AA 1-188)
Quick Overview for RHOH 抗体 (AA 1-188) (ABIN7168038)
抗原
See all RHOH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-188
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Rho-related GTP-binding protein RhoH protein (1-188AA)
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亚型
- IgG
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anti-Ras Homolog Family Member H (RHOH) (C-Term) antibody
RHOH 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Family Member H (RHOH) antibodyRHOH 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Family Member H (RHOH) (AA 141-190) antibodyRHOH 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Family Member H (RHOH) (Internal Region) antibodyRHOH 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Family Member H (RHOH) (AA 1-191) antibodyRHOH 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Family Member H (RHOH) antibodyRHOH 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Family Member H (RHOH) (AA 1-191) antibodyRHOH 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3D3 unconjugated
anti-Ras Homolog Family Member H (RHOH) (AA 1-191) antibodyRHOH 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ras Homolog Family Member H (RHOH) (AA 141-190) antibodyRHOH 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Family Member H (RHOH) (C-Term) antibodyRHOH 适用: 人, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RHOH (Ras Homolog Family Member H (RHOH))
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别名
- RHOH
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背景
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Background: Negative regulator of hematopoietic progenitor cell proliferation, survival and migration. Critical regulator of thymocyte development and T-cell antigen receptor (TCR) signaling by mediating recruitment and activation of ZAP70. Required for phosphorylation of CD3Z, membrane translocation of ZAP70 and subsequent activation of the ZAP70-mediated pathways. Essential for efficient beta-selection and positive selection by promoting the ZAP70-dependent phosphorylation of the LAT signalosome during pre-TCR and TCR signaling. Crucial for thymocyte maturation during DN3 to DN4 transition and during positive selection. Plays critical roles in mast cell function by facilitating phosphorylation of SYK in Fc epsilon RI-mediated signal transduction. Essential for the phosphorylation of LAT, LCP2, PLCG1 and PLCG2 and for Ca(2+) mobilization in mast cells. Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. Inhibits the activation of NF-kappa-B by TNF and IKKB and the activation of CRK/p38 by TNF. Inhibits activities of RAC1, RHOA and CDC42. Negatively regulates leukotriene production in neutrophils.
Aliases: ARHH antibody, GTP binding protein TTF antibody, GTP-binding protein TTF antibody, OTTHUMP00000125213 antibody, Ras homolog gene family member H antibody, Rho related GTP binding protein antibody, Rho related GTP binding protein RhoH antibody, Rho-related GTP-binding protein RhoH antibody, RHOH antibody, RHOH_HUMAN antibody, Translocation three four protein antibody, TTF antibody, TTF translocation three four antibody
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UniProt
- Q15669
抗原
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