RHOB 抗体 (AA 1-196) (FITC)
Quick Overview for RHOB 抗体 (AA 1-196) (FITC) (ABIN7168020)
抗原
See all RHOB 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-196
-
交叉反应
- 人
-
纯化方法
- >95%, Protein G purified
-
免疫原
- Recombinant Human Rho-related GTP-binding protein RhoB protein (1-196AA)
-
亚型
- IgG
-
-
-
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- RHOB (Ras Homolog Gene Family, Member B (RHOB))
-
别名
- RHOB
-
背景
-
Background: Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.
Aliases: Aplysia RAS-related homolog 6 antibody, ARH6 antibody, ARHB antibody, H6 antibody, MST081 antibody, MSTP081 antibody, oncogene RHO H6 antibody, ras homolog family member B antibody, ras homolog gene family, member B antibody, Rho cDNA clone 6 antibody, Rho related GTP binding protein RhoB Precursor antibody, Rho-related GTP-binding protein RhoB antibody, Rhob antibody, RHOB_HUMAN antibody, RHOH6 antibody
-
UniProt
- P62745
抗原
-