ARHGAP18 抗体 (AA 389-577) (HRP)
Quick Overview for ARHGAP18 抗体 (AA 389-577) (HRP) (ABIN7167938)
抗原
See all ARHGAP18 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 389-577
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Rho GTPase-activating protein 18 protein (389-577AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))
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别名
- ARHGAP18
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背景
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Background: Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state (PubMed:21865595). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1 (PubMed:25778702). Regulates cell shape, spreading, and migration (PubMed:21865595).
Aliases: 4833419J07Rik antibody, AI314906 antibody, AI843501 antibody, Arhgap18 antibody, bA307O14.2 antibody, FLJ25728 antibody, MacGAP antibody, MGC126757 antibody, MGC138145 antibody, OTTHUMP00000017190 antibody, OTTMUSP00000028606 antibody, RHG18_HUMAN antibody, Rho GTPase-activating protein 18 antibody, Rho-type GTPase-activating protein 18 antibody, SENEX antibody
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UniProt
- Q8N392
抗原
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