RPE65 抗体 (AA 348-484)
Quick Overview for RPE65 抗体 (AA 348-484) (ABIN7167824)
抗原
See all RPE65 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 348-484
-
交叉反应
- 人, 大鼠
-
纯化方法
- >95%, Protein G purified
-
免疫原
- Recombinant Human Retinoid isomerohydrolase protein (348-484AA)
-
亚型
- IgG
-
-
-
-
应用备注
- Recommended dilution: WB:1:500-1:5000, IF:1:200-1:500,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))
-
别名
- RPE65
-
背景
-
Background: Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association.
Aliases: All-trans-retinyl-palmitate hydrolase antibody, LCA 2 antibody, LCA2 antibody, Leber congenital amaurosis antibody, mRPE 65 antibody, mRPE65 antibody, p63 antibody, rd 12 antibody, rd12 antibody, Retinal pigment epithelium specific 61 kDa protein antibody, Retinal pigment epithelium specific 65 kDa protein antibody, Retinal pigment epithelium specific protein antibody, Retinal pigment epithelium specific protein 65 kDa antibody, Retinal pigment epithelium-specific 65 kDa protein antibody, Retinitis pigmentosa 20 antibody, Retinoid isomerohydrolase antibody, Retinol isomerase antibody, RP 20 antibody, RP20 antibody, RPE 65 antibody, RPE65 antibody, RPE65_HUMAN antibody, sRPE 65 antibody, sRPE65 antibody
-
UniProt
- Q16518
抗原
-