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p107 抗体 (AA 201-500) (Biotin)

This anti-p107 antibody is a 兔 多克隆 antibody detecting p107 in ELISA. Suitable for 人.
产品编号 ABIN7167788
发货至: 中国

Quick Overview for p107 抗体 (AA 201-500) (Biotin) (ABIN7167788)

抗原

See all p107 (RBL1) 抗体
p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))

适用

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宿主

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克隆类型

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多克隆

标记

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This p107 antibody is conjugated to Biotin

应用范围

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ELISA
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    AA 201-500

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Retinoblastoma-like protein 1 protein (201-500AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))

    别名

    RBL1

    背景

    Background: Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 \'Lys-20\' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. May act as a tumor suppressor.

    Aliases: 107 kDa retinoblastoma-associated protein antibody, Cellular protein 107 antibody, Cellular protein p107 antibody, CP107 antibody, MGC40006 antibody, p107 antibody, PRB1 antibody, RBL1 antibody, RBL1_HUMAN antibody, Retinoblastoma like protein 1 antibody, retinoblastoma-like 1 (p107) antibody, Retinoblastoma-like protein 1 antibody

    UniProt

    P28749

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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