RTEL1 抗体 (AA 975-1219)
Quick Overview for RTEL1 抗体 (AA 975-1219) (ABIN7167648)
抗原
See all RTEL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 975-1219
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Regulator of telomere elongation helicase 1 protein (975-1219AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))
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别名
- RTEL1
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背景
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Background: ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.
Aliases: RTEL1 antibody, C20orf41 antibody, KIAA1088 antibody, NHLRegulator of telomere elongation helicase 1 antibody, EC 3.6.4.12 antibody, Novel helicase-like antibody
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UniProt
- Q9NZ71
抗原
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