RPRD1B 抗体 (AA 2-172)
Quick Overview for RPRD1B 抗体 (AA 2-172) (ABIN7167582)
抗原
See all RPRD1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-172
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Regulation of nuclear pre-mRNA domain-containing protein 1B protein (2-172AA)
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亚型
- IgG
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anti-Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B) (AA 1-326) antibody
RPRD1B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D6 unconjugated
anti-Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B) (AA 143-192) antibodyRPRD1B 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 小鸡, 猴, Bat, Hamster, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B) (AA 254-282), (C-Term) antibodyRPRD1B 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB25222 unconjugated
anti-Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B) (AA 261-290), (C-Term) antibodyRPRD1B 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RPRD1B (Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B))
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别名
- RPRD1B
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背景
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Background: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3\' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.
Aliases: RPRD1B antibody, C20orf77 antibody, CREPT antibody, Regulation of nuclear pre-mRNA domain-containing protein 1B antibody, Cell cycle-related and expression-elevated protein in tumor antibody
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UniProt
- Q9NQG5
抗原
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