REST 抗体 (AA 250-350) (HRP)
Quick Overview for REST 抗体 (AA 250-350) (HRP) (ABIN7167428)
抗原
See all REST 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 250-350
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                                            交叉反应
- 人
- 
                                            纯化方法
- >95%, Protein G purified
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                                            免疫原
- Recombinant Human RE1-silencing transcription factor protein (250-350AA)
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                                            亚型
- IgG
 
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                                            应用备注
- Optimal working dilution should be determined by the investigator.
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            缓冲液
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                        Preservative: 0.03 % Proclin 300
 Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C,-80 °C
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                                            储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
 
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    - REST (RE1-Silencing Transcription Factor (REST))
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                                            别名
- REST
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                                            背景
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                        Background: Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. Transcriptional repression by REST-CDYL via the recruitment of histone methyltransferase EHMT2 may be important in transformation suppression. Aliases: Neural Restrictive Silencer Factor antibody, Neural-restrictive silencer factor antibody, Neuron Restrictive Silencer Factor antibody, NRSF antibody, RE1 silencing transcription factor antibody, RE1-silencing transcription factor antibody, Repressor binding to the X2 box antibody, rest antibody, REST protein antibody, REST_HUMAN antibody, X2 box repressor antibody, XBR antibody 
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                                            UniProt
- Q13127
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                                            途径
- Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity
 抗原
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