rala 抗体 (AA 1-203) (FITC)
Quick Overview for rala 抗体 (AA 1-203) (FITC) (ABIN7167392)
抗原
See all rala 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-203
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Ras-related protein Ral-A protein (1-203AA)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- rala (Ras-related Protein Ral-A (rala))
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别名
- RALA
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背景
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Background: Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.
Aliases: MGC48949 antibody, Ral a antibody, Ral A protein antibody, RAL antibody, RALA antibody, RALA_HUMAN antibody, Ras family small GTP binding protein RALA antibody, RAS like protein A antibody, Ras related protein RalA antibody, Ras-related protein Ral-A antibody, v ral simian leukemia viral oncogene homolog A (ras related) antibody, v ral simian leukemia viral oncogene homolog A antibody
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UniProt
- P11233
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途径
- Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
抗原
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