RAB7B 抗体 (AA 100-199) (FITC)
Quick Overview for RAB7B 抗体 (AA 100-199) (FITC) (ABIN7167383)
抗原
See all RAB7B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-199
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Ras-related protein Rab-7b protein (100-199AA)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))
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别名
- RAB7B
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背景
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Background: Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.
Aliases: MGC16212 antibody, MGC9726 antibody, RAB7 antibody, rab7B antibody, RAB7B, member RAS oncogene family antibody, RAB7B_HUMAN antibody, Ras related protein Rab 7b antibody, Ras-related protein Rab-7B antibody
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UniProt
- Q96AH8
抗原
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