RAB11B 抗体 (AA 2-215) (HRP)
Quick Overview for RAB11B 抗体 (AA 2-215) (HRP) (ABIN7167228)
抗原
See all RAB11B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-215
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Ras-related protein Rab-11B protein (2-215AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RAB11B (RAB11B, Member RAS Oncogene Family (RAB11B))
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别名
- RAB11B
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背景
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Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage-gated channel, and voltage-dependent L-type calcium channel. May also regulate constitutive and regulated secretion, like insulin granule exocytosis. Required for melanosome transport and release from melanocytes. Also regulates V-ATPase intracellular transport in response to extracellular acidosis.
Aliases: GTP binding protein YPT3 antibody, GTP-binding protein ypt3 antibody, H-YPT3 antibody, RAB 11A antibody, RAB11B antibody, RAB11B member RAS oncogene family antibody, RAB11B, member of RAS oncogene family antibody, Ras related protein Rab 11B antibody, RAS-associated protein RAB11B antibody, Ras-related protein Rab-11B antibody, RB11B_HUMAN antibody, YPT3 antibody
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UniProt
- Q15907
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途径
- Hormone Transport, Carbohydrate Homeostasis
抗原
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