RASSF5 抗体 (AA 1-265)
Quick Overview for RASSF5 抗体 (AA 1-265) (ABIN7167138)
抗原
See all RASSF5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-265
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Ras association domain-containing protein 5 protein (1-265AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))
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别名
- RASSF5
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背景
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Background: Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.
Aliases: Maxp 1 antibody, MAXP1 antibody, MGC10823 antibody, MGC17344 antibody, New ras effector 1 antibody, NORE 1 antibody, NORE1 antibody, NORE1A antibody, NORE1B antibody, Novel Ras effector 1 antibody, RAP1 Binding Protein antibody, RAPL antibody, Ras association (RalGDS/AF 6) domain family 5 antibody, Ras association (RalGDS/AF 6) domain family member 5 antibody, Ras association domain containing family protein 5 antibody, Ras association domain-containing protein 5 antibody, Ras effector like protein antibody, RASF5_HUMAN antibody, RASSF 3 antibody, RASSF 5 antibody, RASSF3 antibody, RASSF5 antibody, Regulator for cell adhesion and polarization enriched in lymphoid tissue antibody, Regulator for cell adhesion and polarization enriched in lymphoid tissues antibody, Tumor suppressor RASSF3 antibody
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UniProt
- Q8WWW0
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途径
- TCR Signaling
抗原
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