RASSF1 抗体 (AA 23-145)
Quick Overview for RASSF1 抗体 (AA 23-145) (ABIN7167122)
抗原
See all RASSF1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 23-145
-
交叉反应
- 人
-
纯化方法
- >95%, Protein G purified
-
免疫原
- Recombinant Human Ras association domain-containing protein 1 protein (23-145AA)
-
亚型
- IgG
-
-
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 145-260) antibody
RASSF1 适用: 人, 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (Internal Region) antibodyRASSF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 101-340) antibodyRASSF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 1-340) antibodyRASSF1 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (Center) antibodyRASSF1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 1-340) antibodyRASSF1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 1-340), (Isoform A), (N-Term) antibodyRASSF1 适用: 人 WB, IF, EIA 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 1-270) antibodyRASSF1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 201-250) antibodyRASSF1 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 绵羊, 斑马鱼, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (C-Term) antibodyRASSF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Recommended dilution: IHC:1:20-1:200,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
-
别名
- RASSF1
-
背景
-
Background: Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Isoform A interacts with CDC20, an activator of the anaphase-promoting complex, APC, resulting in the inhibition of APC activity and mitotic progression. Inhibits proliferation by negatively regulating cell cycle progression at the level of G1/S-phase transition by regulating accumulation of cyclin D1 protein. Isoform C has been shown not to perform these roles, no function has been identified for this isoform. Isoform A disrupts interactions among MDM2, DAXX and USP7, thus contributing to the efficient activation of TP53 by promoting MDM2 self-ubiquitination in cell-cycle checkpoint control in response to DNA damage.
Aliases: 123F2 antibody, Cardiac specific ras association domain family 1 protein antibody, cardiac-specific ras association domain family 1 protein, 123F2 antibody, NORE2A antibody, OTTHUMP00000195503 antibody, OTTHUMP00000195504 antibody, OTTHUMP00000195505 antibody, OTTHUMP00000195507 antibody, Pancreas specific ras association domain family 1 protein antibody, Ras association (RalGDS/AF 6) domain family member 1 antibody, Ras association domain-containing protein 1 antibody, RASF1_HUMAN antibody, Rassf1 antibody, RASSF1A antibody, RDA32 antibody, REH3P21 antibody, Tumor suppressor protein RDA32 antibody, WUGSC:H_LUCA12.5 antibody
-
UniProt
- Q9NS23
抗原
-
