RIN1 抗体 (AA 192-341)
Quick Overview for RIN1 抗体 (AA 192-341) (ABIN7167114)
抗原
See all RIN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 192-341
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Ras and Rab interactor 1 protein (192-341AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RIN1 (Ras and Rab Interactor 1 (RIN1))
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别名
- RIN1
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背景
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Background: Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.
Aliases: RIN1 antibody, Ras and Rab interactor 1 antibody, Ras inhibitor JC99 antibody, Ras interaction/interference protein 1 antibody
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UniProt
- Q13671
抗原
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