RanBP3 抗体 (AA 1-250)
Quick Overview for RanBP3 抗体 (AA 1-250) (ABIN7167094)
抗原
See all RanBP3 (RANBP3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-250
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Ran-binding protein 3 protein (1-250AA)
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亚型
- IgG
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anti-RAN Binding Protein 3 (RANBP3) (AA 298-397) antibody
RANBP3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-RAN Binding Protein 3 (RANBP3) (AA 1-250) antibodyRANBP3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))
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别名
- RANBP3
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背景
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Background: Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.
Aliases: DKFZp586I1520 antibody, Ran binding protein 3 antibody, Ran-binding protein 3 antibody, RANB3_HUMAN antibody, RanBP3 antibody
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UniProt
- Q9H6Z4
抗原
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