HBXIP 抗体 (AA 1-91)
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北京 101111
Quick Overview for HBXIP 抗体 (AA 1-91) (ABIN7167073)
抗原
See all HBXIP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-91
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原理
- LAMTOR5 Antibody
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Ragulator complex protein LAMTOR5 protein (1-91AA)
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亚型
- IgG
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anti-Hepatitis B Virus X-Interacting Protein (HBXIP) (AA 83-173) antibody
HBXIP 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G1 unconjugated
anti-Hepatitis B Virus X-Interacting Protein (HBXIP) (AA 1-173) antibodyHBXIP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Hepatitis B Virus X-Interacting Protein (HBXIP) (AA 41-91) antibodyHBXIP 适用: 人 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hepatitis B Virus X-Interacting Protein (HBXIP) (AA 83-173) antibodyHBXIP 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Hepatitis B Virus X-Interacting Protein (HBXIP) (AA 83-173) antibodyHBXIP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D3 unconjugated
anti-Hepatitis B Virus X-Interacting Protein (HBXIP) (N-Term) antibodyHBXIP 适用: Hepatitis B Virus (HBV) WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))
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别名
- LAMTOR5
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物质类
- Viral Protein
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背景
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Background: As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication.
Aliases: HBV X interacting protein antibody, HBV X-interacting protein antibody, HBX interacting protein antibody, HBX-interacting protein antibody, hbxip antibody, HBXIP_HUMAN antibody, Hepatitis B virus X interacting protein antibody, Hepatitis B virus X-interacting protein antibody, LAMTOR5 antibody, Late endosomal/lysosomal adaptor MAPK and MTOR activator 5 antibody, MGC71071 antibody, Ragulator complex protein LAMTOR5 antibody, XIP antibody
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UniProt
- O43504
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途径
- PI3K-Akt Signaling, Regulation of Cell Size
抗原
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