MAPKSP1 抗体 (AA 1-124)
Quick Overview for MAPKSP1 抗体 (AA 1-124) (ABIN7167072)
抗原
See all MAPKSP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-124
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Ragulator complex protein LAMTOR3 protein (1-124AA)
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1) antibody
MAPKSP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1) (AA 1-124) antibodyMAPKSP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1) (AA 1-87) antibodyMAPKSP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1) (Internal Region) antibodyMAPKSP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1) (AA 13-62) antibodyMAPKSP1 适用: 人, Cow, 马, 兔, 小鸡, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))
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别名
- LAMTOR3
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背景
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Background: As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.
Aliases: LAMTOR3 antibody, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3 antibody, LTOR3_HUMAN antibody, MAP2K1IP1 antibody, MEK binding partner 1 antibody, MEK partner 1 antibody, MEK-binding partner 1 antibody, Mitogen activated protein kinase kinase 1 interacting protein 1 antibody, Mitogen-activated protein kinase kinase 1-interacting protein 1 antibody, Mitogen-activated protein kinase scaffold protein 1 antibody, Mp1 antibody, Ragulator complex protein LAMTOR3 antibody
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UniProt
- Q9UHA4
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途径
- PI3K-Akt Signaling
抗原
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