R-Spondin 3 抗体 (AA 22-272)
Quick Overview for R-Spondin 3 抗体 (AA 22-272) (ABIN7166936)
抗原
See all R-Spondin 3 (RSPO3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 22-272
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human R-spondin-3 protein (22-272AA)
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亚型
- IgG
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anti-R-Spondin 3 (RSPO3) (AA 22-272) antibody
RSPO3 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 3 (RSPO3) (AA 197-230) antibodyRSPO3 适用: 人 WB 宿主: 兔 Polyclonal RB54572 unconjugated
anti-R-Spondin 3 (RSPO3) (AA 214-248) antibodyRSPO3 适用: 人 WB 宿主: 兔 Polyclonal RB54573 unconjugated
anti-R-Spondin 3 (RSPO3) (AA 202-251) antibodyRSPO3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 3 (RSPO3) (AA 1-100) antibodyRSPO3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- R-Spondin 3 (RSPO3)
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别名
- RSPO3
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背景
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Background: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.
Aliases: CRISTIN1 antibody, hPWTSR antibody, hRspo3 antibody, Protein with TSP type-1 repeat antibody, PWTSR antibody, R-spondin 3 homolog antibody, R-spondin-3 [Precursor] antibody, R-spondin-3 antibody, Roof plate specific spondin-3 antibody, Roof plate-specific spondin-3 antibody, RSPO3 antibody, RSPO3_HUMAN antibody, Thrombospondin type I domain containing 2 antibody, Thrombospondin type-1 domain-containing protein 2 antibody, THSD2 antibody
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UniProt
- Q9BXY4
抗原
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