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RSPO1 抗体 (AA 21-263)

This anti-RSPO1 antibody is a 兔 多克隆 antibody detecting RSPO1 in IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7166935
发货至: 中国

Quick Overview for RSPO1 抗体 (AA 21-263) (ABIN7166935)

抗原

See all RSPO1 抗体
RSPO1 (R-Spondin 1 (RSPO1))

适用

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  • 15
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宿主

  • 54
  • 8
  • 1

克隆类型

  • 55
  • 8
多克隆

标记

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This RSPO1 antibody is un-conjugated

应用范围

  • 45
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Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 15
    • 11
    • 6
    • 3
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    • 1
    • 1
    • 1
    AA 21-263

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human R-spondin-1 protein (21-263AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    RSPO1 (R-Spondin 1 (RSPO1))

    别名

    RSPO1

    背景

    Background: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determination.

    Aliases: CRISTIN3, FLJ40906, hRspo1, R spondin homolog, R spondin homolog (Xenopus laevis), R spondin1, R-spondin-1, Roof plate specific spondin, Roof plate-specific spondin-1, RP11-566C13.1, RSPO, Rspo1, RSPO1_HUMAN

    UniProt

    Q2MKA7
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