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QTRT1 抗体 (Catalytic Subunit 1) (Biotin)

This anti-QTRT1 antibody is a 兔 多克隆 antibody detecting QTRT1 in ELISA. Suitable for 人.
产品编号 ABIN7166919
发货至: 中国

Quick Overview for QTRT1 抗体 (Catalytic Subunit 1) (Biotin) (ABIN7166919)

抗原

See all QTRT1 抗体
QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))

适用

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宿主

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克隆类型

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多克隆

标记

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This QTRT1 antibody is conjugated to Biotin

应用范围

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ELISA
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    AA 211-403, Catalytic Subunit 1

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Queuine tRNA-ribosyltransferase catalytic subunit 1 protein (211-403AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))

    别名

    QTRT1

    背景

    Background: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GUN anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (PubMed:11255023, PubMed:20354154). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1\' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1\' of the ribose to form the product (By similarity).

    Aliases: FP3235 antibody, Guanine insertion enzyme antibody, qtrt1 antibody, Queuine tRNA ribosyltransferase 1 antibody, Queuine tRNA ribosyltransferase antibody, Queuine tRNA-ribosyltransferase antibody, TGT antibody, TGT, 43 KD subunit antibody, TGT, catalytic subunit antibody, TGT_HUMAN antibody, TGUT antibody, tRNA guanine transglycosylase antibody, tRNA-guanine transglycosylase antibody

    UniProt

    Q9BXR0

    途径

    Ribonucleoside Biosynthetic Process
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