QTRT1 抗体 (Catalytic Subunit)
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北京 101111
Quick Overview for QTRT1 抗体 (Catalytic Subunit) (ABIN7166918)
抗原
See all QTRT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 211-403, Catalytic Subunit
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原理
- QTRT1 Antibody
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human Queuine tRNA-ribosyltransferase catalytic subunit 1 protein (211-403AA)
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亚型
- IgG
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anti-Queuine tRNA-Ribosyltransferase 1 (QTRT1) (AA 1-358) antibody
QTRT1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Queuine tRNA-Ribosyltransferase 1 (QTRT1) antibodyQTRT1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Queuine tRNA-Ribosyltransferase 1 (QTRT1) (AA 22-340) antibodyQTRT1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Queuine tRNA-Ribosyltransferase 1 (QTRT1) (AA 252-301) antibodyQTRT1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 斑马鱼, 豚鼠, Bat, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Queuine tRNA-Ribosyltransferase 1 (QTRT1) (AA 45-94) antibodyQTRT1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 斑马鱼, 兔, Bat, 猴, Drosophila melanogaster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))
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别名
- QTRT1
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背景
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Background: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GUN anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (PubMed:11255023, PubMed:20354154). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1\\\' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1\\\' of the ribose to form the product (By similarity).
Aliases: FP3235 antibody, Guanine insertion enzyme antibody, qtrt1 antibody, Queuine tRNA ribosyltransferase 1 antibody, Queuine tRNA ribosyltransferase antibody, Queuine tRNA-ribosyltransferase antibody, TGT antibody, TGT, 43 KD subunit antibody, TGT, catalytic subunit antibody, TGT_HUMAN antibody, TGUT antibody, tRNA guanine transglycosylase antibody, tRNA-guanine transglycosylase antibody
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UniProt
- Q9BXR0
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途径
- Ribonucleoside Biosynthetic Process
抗原
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