PYHIN1 抗体 (AA 1-245)
Quick Overview for PYHIN1 抗体 (AA 1-245) (ABIN7166880)
抗原
See all PYHIN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-245
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交叉反应
- 人, 小鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Pyrin and HIN domain-containing protein 1 protein (1-245AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:1000-1:5000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
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别名
- PYHIN1
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背景
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Background: Major mediator of the tumor suppressor activity of IFN in breast cancer cells. Promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization. Promotes ubiquitination and subsequent degradation of HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
Aliases: IFIX_HUMAN antibody, Interferon-inducible protein X antibody, Pyhin1 antibody, Pyrin and HIN domain-containing protein 1 antibody
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UniProt
- Q6K0P9
抗原
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