MCF2 抗体 (AA 705-925) (FITC)
Quick Overview for MCF2 抗体 (AA 705-925) (FITC) (ABIN7166482)
抗原
See all MCF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 705-925
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Proto-oncogene DBL protein (705-925AA)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MCF2 (MCF.2 Cell Line Derived Transforming Sequence (MCF2))
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别名
- MCF2
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背景
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Background: Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases. Promotes the conversion of some member of the Rho family GTPase from the GDP-bound to the GTP-bound form. Isoform 1 exhibits no activity toward RHOA, RAC1 or CDC42. Isoform 2 exhibits decreased GEF activity toward CDC42. Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42. Isoform 4 exhibits significant activity toward RHOA and CDC42. The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42.
Aliases: MCF2 antibody, DBLProto-oncogene DBL antibody, Proto-oncogene MCF-2) [Cleaved into: MCF2-transforming protein, DBL-transforming protein] antibody
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UniProt
- P10911
抗原
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