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UXT 抗体 (AA 1-157)

This 兔 多克隆 antibody specifically detects UXT in WB, IHC 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN7166273
发货至: 中国
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Quick Overview for UXT 抗体 (AA 1-157) (ABIN7166273)

抗原

See all UXT 抗体
UXT (Ubiquitously-Expressed, Prefoldin-Like Chaperone (UXT))

适用

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宿主

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克隆类型

  • 27
多克隆

标记

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This UXT antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 6
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    AA 1-157

    原理

    UXT Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Protein UXT protein (1-157AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    UXT (Ubiquitously-Expressed, Prefoldin-Like Chaperone (UXT))

    别名

    UXT

    背景

    Background: Involved in gene transcription regulation. Acts in concert with the corepressor URI1 to regulate androgen receptor transcription (AR). AR N-terminus-associated coactivator which may play a role in facilitating receptor-induced transcriptional activation (PubMed:11854421). Potential component of mitochondrial-associated LRPPRC, a multidomain organizer that potentially integrates mitochondria and the microtubular cytoskeleton with chromosome remodeling (PubMed:11827465). Increasing concentrations of UXT contributes to progressive aggregation of mitochondria and cell death potentially through its association with LRPPRC (PubMed:17554592). May be a nuclear chaperone that promotes formation of the NF-kappa-B enhanceosome and which is essential for its nuclear function (PubMed:17620405). Suppresses cell transformation and it might mediate this function by interaction and inhibition of the biological activity of cell proliferation and survival stimulatory factors like MECOM (PubMed:17635584). Together with URI1, associates with chromatin to the NKX3-1 promoter region.

    Aliases: Androgen receptor trapped clone 27 protein antibody, ART 27 antibody, ART-27 antibody, OTTHUMP00000023226 antibody, OTTHUMP00000023227 antibody, Protein UXT antibody, SKP2 associated alpha PFD 1 antibody, STAP1 antibody, Ubiquitously expressed prefoldin like chaperone antibody, Ubiquitously expressed transcript antibody, Ubiquitously expressed transcript protein antibody, Uxt antibody, UXT_HUMAN antibody

    UniProt

    Q9UBK9

    途径

    Unfolded Protein Response
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