S100A12 抗体 (AA 2-91)
Quick Overview for S100A12 抗体 (AA 2-91) (ABIN7166043)
抗原
See all S100A12 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 2-91
-
原理
- S100A12 Antibody
-
纯化方法
- Antigen Affinity purified & Affinity purified
-
纯度
- >95 %
-
免疫原
- Recombinant Human Protein S100-A12 protein (2-91AA)
-
亚型
- IgG
-
-
anti-S100 Calcium Binding Protein A12 (S100A12) (AA 1-92) antibody
S100A12 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A12 (S100A12) (AA 2-92) antibodyS100A12 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A12 (S100A12) (AA 2-92) antibodyS100A12 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A12 (S100A12) (AA 1-92) antibodyS100A12 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A12 (S100A12) antibodyS100A12 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-812M unconjugated
anti-S100 Calcium Binding Protein A12 (S100A12) (AA 1-92) antibodyS100A12 适用: 人 WB 宿主: 小鼠 Monoclonal 15# unconjugated
anti-S100 Calcium Binding Protein A12 (S100A12) antibodyS100A12 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A12 (S100A12) (AA 1-92) antibodyS100A12 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F10 unconjugated
anti-S100 Calcium Binding Protein A12 (S100A12) antibodyS100A12 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A12 (S100A12) antibodyS100A12 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- S100A12 (S100 Calcium Binding Protein A12 (S100A12))
-
别名
- S100A12
-
背景
-
Background: S100A12 is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. Its proinflammatory activity involves recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. Acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to receptor for advanced glycation endproducts (AGER). Binding to AGER activates the MAP-kinase and NF-kappa-B signaling pathways leading to production of proinflammatory cytokines and up-regulation of cell adhesion molecules ICAM1 and VCAM1. Acts as a monocyte and mast cell chemoattractant. Can stimulate mast cell degranulation and activation which generates chemokines, histamine and cytokines inducing further leukocyte recruitment to the sites of inflammation. Can inhibit the activity of matrix metalloproteinases, MMP2, MMP3 and MMP9 by chelating Zn(2+) from their active sites. Possesses filariacidal and filariastatic activity. Calcitermin possesses antifungal activity against C.albicans and is also active against E.coli and P.aeruginosa but not L.monocytogenes and S.aureus.
Aliases: CAAF1 antibody, CAGC antibody, Calcitermin antibody, Calcium-binding protein in amniotic fluid 1 antibody, Calgranulin C antibody, Calgranulin-C antibody, Calgranulin-related protein antibody, CGRP antibody, EN RAGE antibody, EN-RAGE antibody, ENRAGE antibody, Extracellular newly identified RAGE-binding protein antibody, migration inhibitory factor-related protein 6 antibody, MRP6 antibody, Neutrophil S100 protein antibody, p6 antibody, Protein S100 A12 antibody, S100 calcium binding protein A12 antibody, S100 calcium-binding protein A12 (calgranulin C) antibody, S100 calcium-binding protein A12 antibody, S100A12 antibody, S10AC_HUMAN antibody
-
UniProt
- P80511
-
途径
- Toll-Like Receptors Cascades, S100 Proteins
抗原
-
