LIN7A 抗体 (AA 1-233) (HRP)
Quick Overview for LIN7A 抗体 (AA 1-233) (HRP) (ABIN7165761)
抗原
See all LIN7A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-233
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Protein lin-7 homolog A protein (1-233AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- LIN7A (Lin-7 Homolog A (LIN7A))
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别名
- LIN7A
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背景
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Background: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
Aliases: hLin-7 antibody, Lin 7 homolog A (C. elegans) antibody, LIN 7A antibody, Lin-7A antibody, LIN7 antibody, LIN7A antibody, LIN7A_HUMAN antibody, MALS-1 antibody, Mammalian LIN 7 1 antibody, Mammalian lin-seven protein 1 antibody, Protein lin-7 homolog A antibody, Tax interaction protein 33 antibody, TIP-33 antibody, Veli-1 antibody, VELI1 antibody, Vertebrate lin-7 homolog 1 antibody, Vertebrate LIN7 homolog 1 antibody
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UniProt
- O14910
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途径
- Synaptic Membrane
抗原
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