HOOK3 抗体 (AA 357-455)
Quick Overview for HOOK3 抗体 (AA 357-455) (ABIN7165641)
抗原
See all HOOK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 357-455
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Protein Hook homolog 3 protein (357-455AA)
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亚型
- IgG
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anti-Hook Homolog 3 (HOOK3) (AA 622-718) antibody
HOOK3 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3A5 unconjugated
anti-Hook Homolog 3 (HOOK3) (AA 489-718) antibodyHOOK3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Hook Homolog 3 (HOOK3) (AA 1-718) antibodyHOOK3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IP:1:200-1:2000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- HOOK3 (Hook Homolog 3 (HOOK3))
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别名
- HOOK3
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背景
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Background: Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:25035494).
Aliases: FLJ31058 antibody, h-hook3 antibody, hHK3 antibody, HK3 antibody, hook3 antibody, HOOK3_HUMAN antibody, OTTHUMP00000229200 antibody, Protein Hook homolog 3 antibody
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UniProt
- Q86VS8
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途径
- Stem Cell Maintenance, Maintenance of Protein Location
抗原
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