CBFA2T3 抗体 (AA 39-159) (Biotin)
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- 抗原 See all CBFA2T3 抗体
- CBFA2T3 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3))
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抗原表位
- AA 39-159
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CBFA2T3 antibody is conjugated to Biotin
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Protein CBFA2T3 protein (39-159AA)
- 亚型
- IgG
- Top Product
- Discover our top product CBFA2T3 Primary Antibody
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anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3) (AA 1-615) antibody
CBFA2T3 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3) (N-Term) antibodyCBFA2T3 适用: 人, 小鼠, 大鼠, 豚鼠, 马, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3) (AA 39-159) antibodyCBFA2T3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3) (N-Term) antibodyCBFA2T3 适用: 人, 小鼠, 大鼠, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3) (AA 418-653) antibodyCBFA2T3 适用: 人 WB 宿主: 小鼠 Monoclonal 1719CT425-37-65 unconjugated
anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3) antibodyCBFA2T3 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3) (N-Term) antibodyCBFA2T3 适用: 人, 小鼠, 大鼠, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3) (AA 305-390) antibodyCBFA2T3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CBFA2T3 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3))
- 别名
- CBFA2T3 (CBFA2T3 产品)
- 别名
- A630044F12Rik antibody, AI465270 antibody, AW229127 antibody, Cbfa2t3h antibody, ETO-2 antibody, Eto2 antibody, MTGR2 antibody, MTG16a antibody, MTG16b antibody, ETO2 antibody, MTG16 antibody, ZMYND4 antibody, core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human) antibody, CBFA2/RUNX1 translocation partner 3 antibody, Cbfa2t3 antibody, CBFA2T3 antibody
- 背景
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Background: Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes (PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner (PubMed:23251453). Reduces the protein levels and stability of the transcriptinal regulator HIF1A, interacts with EGLN1 and promotes the HIF1A prolyl hydroxylation-dependent ubiquitination and proteasomal degradation pathway (PubMed:25974097). Contributes to inhibition of glycolysis and stimulation of mitochondrial respiration by down-regulating the expression of glycolytic genes including PFKFB3, PFKFB4, PDK1, PFKP, LDHA and HK1 which are direct targets of HIF1A (PubMed:23840896, PubMed:25974097). Regulates the proliferation and the differentiation of erythroid progenitors by repressing the expression of TAL1 target genes (By similarity). Plays a role in granulocyte differentiation (PubMed:15231665).
Aliases: Cbfa2t3 antibody, Ccore binding factor runt domain alpha subunit 2 translocated to 3 antibody, ETO2 antibody, hMTG16 antibody, hMTG16a antibody, hMTG16b antibody, MTG16 antibody, MTG16_HUMAN antibody, MTG8 related gene 2 antibody, MTG8 related protein MTG16a antibody, MTG8 related protein MTG16b antibody, MTG8-related protein 2 antibody, MTGR2 antibody, Myeloid translocation gene 8 and 16b antibody, Myeloid translocation gene on chromosome 16 protein antibody, Protein CBFA2T3 antibody, Zinc finger MYND domain-containing protein 4 antibody, ZMYND4 antibody
- UniProt
- O75081
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