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BICD2 抗体 (AA 511-625) (FITC)

BICD2 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7165142
发货至: 中国
  • 抗原 See all BICD2 抗体
    BICD2 (Bicaudal D Homolog 2 (BICD2))
    抗原表位
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 511-625
    适用
    • 24
    • 5
    • 5
    • 2
    • 2
    宿主
    • 22
    • 2
    克隆类型
    • 22
    • 2
    多克隆
    标记
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BICD2 antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Protein bicaudal D homolog 2 protein (511-625AA)
    亚型
    IgG
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    BICD2 (Bicaudal D Homolog 2 (BICD2))
    别名
    BICD2 (BICD2 产品)
    别名
    SMALED2 antibody, bA526D8.1 antibody, 0610027D24Rik antibody, 1110005D12Rik antibody, AA408834 antibody, mKIAA0699 antibody, MGC84972 antibody, BICD2 antibody, bicd2 antibody, BICD cargo adaptor 2 antibody, bicaudal D homolog 2 (Drosophila) antibody, BICD cargo adaptor 2 L homeolog antibody, zgc:171572 antibody, BICD2 antibody, Bicd2 antibody, bicd2.L antibody, bicd2 antibody, zgc:171572 antibody
    背景

    Background: Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (By similarity). Facilitates the binding of RAB6A to the Golgi by stabilizing its GTP-bound form. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport via its interaction with RAB6A and recruitment of the dynein-dynactin motor complex (PubMed:25962623). Contributes to nuclear and centrosomal positioning prior to mitotic entry through regulation of both dynein and kinesin-1. During G2 phase of the cell cycle, associates with RANBP2 at the nuclear pores and recruits dynein and dynactin to the nuclear envelope to ensure proper positioning of the nucleus relative to centrosomes prior to the onset of mitosis (By similarity).

    Aliases: bA526D8.1 antibody, Bic D 2 antibody, Bic-D 2 antibody, Bicaudal D homolog 2 (Drosophila) antibody, Bicaudal D homolog 2 antibody, Bicd2 antibody, BICD2_HUMAN antibody, Coiled coil protein BICD2 antibody, Cytoskeleton like bicaudal D protein homolog 2 antibody, Homolog of Drosophila bicaudal D antibody, KIAA0699 antibody, Protein bicaudal D homolog 2 antibody

    UniProt
    Q8TD16
    途径
    Maintenance of Protein Location
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