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BICD2 抗体 (AA 511-625)

This anti-BICD2 antibody is a 兔 多克隆 antibody detecting BICD2 in WB, ELISA, IHC 和 IF. Suitable for 人.
产品编号 ABIN7165140
发货至: 中国

Quick Overview for BICD2 抗体 (AA 511-625) (ABIN7165140)

抗原

See all BICD2 抗体
BICD2 (Bicaudal D Homolog 2 (BICD2))

适用

  • 25
  • 5
  • 5
  • 2
  • 2

宿主

  • 23
  • 2

克隆类型

  • 23
  • 2
多克隆

标记

  • 16
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This BICD2 antibody is un-conjugated

应用范围

  • 14
  • 6
  • 5
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  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 511-625

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Protein bicaudal D homolog 2 protein (511-625AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    BICD2 (Bicaudal D Homolog 2 (BICD2))

    别名

    BICD2

    背景

    Background: Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (By similarity). Facilitates the binding of RAB6A to the Golgi by stabilizing its GTP-bound form. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport via its interaction with RAB6A and recruitment of the dynein-dynactin motor complex (PubMed:25962623). Contributes to nuclear and centrosomal positioning prior to mitotic entry through regulation of both dynein and kinesin-1. During G2 phase of the cell cycle, associates with RANBP2 at the nuclear pores and recruits dynein and dynactin to the nuclear envelope to ensure proper positioning of the nucleus relative to centrosomes prior to the onset of mitosis (By similarity).

    Aliases: bA526D8.1 antibody, Bic D 2 antibody, Bic-D 2 antibody, Bicaudal D homolog 2 (Drosophila) antibody, Bicaudal D homolog 2 antibody, Bicd2 antibody, BICD2_HUMAN antibody, Coiled coil protein BICD2 antibody, Cytoskeleton like bicaudal D protein homolog 2 antibody, Homolog of Drosophila bicaudal D antibody, KIAA0699 antibody, Protein bicaudal D homolog 2 antibody

    UniProt

    Q8TD16

    途径

    Maintenance of Protein Location
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