BICD2 抗体 (AA 511-625)
Quick Overview for BICD2 抗体 (AA 511-625) (ABIN7165140)
抗原
See all BICD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 511-625
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Protein bicaudal D homolog 2 protein (511-625AA)
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亚型
- IgG
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anti-Bicaudal D Homolog 2 (BICD2) (AA 440-620) antibody
BICD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bicaudal D Homolog 2 (BICD2) (AA 787-818), (C-Term) antibodyBICD2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB15418 unconjugated
anti-Bicaudal D Homolog 2 (BICD2) (C-Term) antibodyBICD2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BICD2 (Bicaudal D Homolog 2 (BICD2))
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别名
- BICD2
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背景
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Background: Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (By similarity). Facilitates the binding of RAB6A to the Golgi by stabilizing its GTP-bound form. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport via its interaction with RAB6A and recruitment of the dynein-dynactin motor complex (PubMed:25962623). Contributes to nuclear and centrosomal positioning prior to mitotic entry through regulation of both dynein and kinesin-1. During G2 phase of the cell cycle, associates with RANBP2 at the nuclear pores and recruits dynein and dynactin to the nuclear envelope to ensure proper positioning of the nucleus relative to centrosomes prior to the onset of mitosis (By similarity).
Aliases: bA526D8.1 antibody, Bic D 2 antibody, Bic-D 2 antibody, Bicaudal D homolog 2 (Drosophila) antibody, Bicaudal D homolog 2 antibody, Bicd2 antibody, BICD2_HUMAN antibody, Coiled coil protein BICD2 antibody, Cytoskeleton like bicaudal D protein homolog 2 antibody, Homolog of Drosophila bicaudal D antibody, KIAA0699 antibody, Protein bicaudal D homolog 2 antibody
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UniProt
- Q8TD16
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途径
- Maintenance of Protein Location
抗原
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