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- 抗原 See all PSMB8 抗体
- PSMB8 (Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8))
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抗原表位
- AA 176-276
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PSMB8 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Proteasome subunit beta type-8 protein (176-276AA)
- 亚型
- IgG
- Top Product
- Discover our top product PSMB8 Primary Antibody
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anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8) (AA 173-272) antibody
PSMB8 适用: 人 WB, ELISA, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8) antibodyPSMB8 适用: 人 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 1A5 unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8) (AA 75-261) antibodyPSMB8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8) (AA 75-272) antibodyPSMB8 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8) (AA 163-272) antibodyPSMB8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8) (AA 80-261) antibodyPSMB8 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8) antibodyPSMB8 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8) (AA 1-272) antibodyPSMB8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8) (Center) antibodyPSMB8 适用: 人, 小鼠 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8) (AA 1-272) antibodyPSMB8 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PSMB8 (Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8))
- 别名
- PSMB8 (PSMB8 产品)
- 背景
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Background: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH . The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB5 by PSMB8 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues. Acts as a major component of interferon gamma-induced sensitivity. Plays a key role in apoptosis via the degradation of the apoptotic inhibitor MCL1. May be involved in the inflammatory response pathway. In cancer cells, substitution of isoform 1 (E2) by isoform 2 (E1) results in immunoproteasome deficiency. Required for the differentiation of preadipocytes into adipocytes.
Aliases: ALDD antibody, D6S216 antibody, D6S216E antibody, Large multifunctional peptidase 7 antibody, Large multifunctional protease 7 antibody, LMP 7 antibody, LMP7 antibody, Low molecular mass protein 7 antibody, Low molecular weight protein 7 antibody, Macropain subunit C13 antibody, MGC1491 antibody, Multicatalytic endopeptidase complex subunit C13 antibody, NKJO antibody, OTTHUMP00000062981 antibody, Protease component C13 antibody, Proteasome (prosome macropain) subunit beta type 8 antibody, Proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) antibody, Proteasome beta 8 subunit antibody, Proteasome catalytic subunit 3i antibody, Proteasome component C13 antibody, Proteasome related gene 7 antibody, Proteasome subunit beta 5i antibody, Proteasome subunit beta 8 antibody, Proteasome subunit beta type 8 antibody, Proteasome subunit beta type antibody, Proteasome subunit beta type-8 antibody, Proteasome subunit beta-5i antibody, Proteasome subunit Y2 antibody, PSB8_HUMAN antibody, PSMB 8 antibody, PSMB5i antibody, PSMB8 antibody, Really interesting new gene 10 protein antibody, RING 10 antibody, RING10 antibody, Y2 antibody
- UniProt
- P28062
- 途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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