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PSMB8 抗体 (AA 176-276)

PSMB8 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7164990
发货至: 中国
  • 抗原 See all PSMB8 抗体
    PSMB8 (Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8))
    抗原表位
    • 16
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 176-276
    适用
    • 61
    • 7
    • 6
    • 1
    • 1
    宿主
    • 55
    • 7
    • 1
    • 1
    克隆类型
    • 57
    • 7
    多克隆
    标记
    • 35
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSMB8 antibody is un-conjugated
    应用范围
    • 46
    • 29
    • 27
    • 15
    • 14
    • 14
    • 12
    • 8
    • 8
    • 7
    • 3
    • 3
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Proteasome subunit beta type-8 protein (176-276AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PSMB8 (Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8))
    别名
    PSMB8 (PSMB8 产品)
    别名
    ALDD antibody, D6S216 antibody, D6S216E antibody, JMP antibody, LMP7 antibody, NKJO antibody, PSMB5i antibody, RING10 antibody, ATP6V0D2 antibody, lmp7 antibody, prosome antibody, macropain antibody, Lmp-7 antibody, Lmp7 antibody, Ring10 antibody, proteasome subunit beta 8 antibody, proteasome subunit beta 8A antibody, proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) antibody, PSMB8 antibody, psmb8a antibody, Psmb8 antibody
    背景

    Background: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH . The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB5 by PSMB8 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues. Acts as a major component of interferon gamma-induced sensitivity. Plays a key role in apoptosis via the degradation of the apoptotic inhibitor MCL1. May be involved in the inflammatory response pathway. In cancer cells, substitution of isoform 1 (E2) by isoform 2 (E1) results in immunoproteasome deficiency. Required for the differentiation of preadipocytes into adipocytes.

    Aliases: ALDD antibody, D6S216 antibody, D6S216E antibody, Large multifunctional peptidase 7 antibody, Large multifunctional protease 7 antibody, LMP 7 antibody, LMP7 antibody, Low molecular mass protein 7 antibody, Low molecular weight protein 7 antibody, Macropain subunit C13 antibody, MGC1491 antibody, Multicatalytic endopeptidase complex subunit C13 antibody, NKJO antibody, OTTHUMP00000062981 antibody, Protease component C13 antibody, Proteasome (prosome macropain) subunit beta type 8 antibody, Proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) antibody, Proteasome beta 8 subunit antibody, Proteasome catalytic subunit 3i antibody, Proteasome component C13 antibody, Proteasome related gene 7 antibody, Proteasome subunit beta 5i antibody, Proteasome subunit beta 8 antibody, Proteasome subunit beta type 8 antibody, Proteasome subunit beta type antibody, Proteasome subunit beta type-8 antibody, Proteasome subunit beta-5i antibody, Proteasome subunit Y2 antibody, PSB8_HUMAN antibody, PSMB 8 antibody, PSMB5i antibody, PSMB8 antibody, Really interesting new gene 10 protein antibody, RING 10 antibody, RING10 antibody, Y2 antibody

    UniProt
    P28062
    途径
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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