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DDX5 抗体 (AA 1-290)

This anti-DDX5 antibody is a 兔 多克隆 antibody detecting DDX5 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7164363
发货至: 中国

Quick Overview for DDX5 抗体 (AA 1-290) (ABIN7164363)

抗原

See all DDX5 抗体
DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))

适用

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宿主

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克隆类型

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多克隆

标记

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This DDX5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-290

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Probable ATP-dependent RNA helicase DDX5 protein (1-290AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))

    别名

    DDX5

    背景

    Background: Involved in the alternative regulation of pre-mRNA splicing, its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation, the function is independent of the RNA helicase activity. Transcriptional coactivator for estrogen receptor ESR1 and androgen receptor AR. Increases ESR1 AF-1 domain-mediated transactivation and ESR1 AF-1 and AF-2 domains transcriptional synergistic activity. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 transcriptional activity and involved in skeletal muscle differentiation. Transcriptional coactivator for p53/TP53 and involved in p53/TP53 transcriptional response to DNA damage and p53/TP53-dependent apoptosis. Transcriptional coactivator for RUNX2 and involved in regulation of osteoblast differentiation. Acts as transcriptional repressor in a promoter-specicic manner, the function probbaly involves association with histone deacetylases, such as HDAC1. As component of a large PER complex is involved in the inhibition of 3\\\' transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms.

    Aliases: ATP dependent RNA helicase DDX5 antibody, DDX 5 antibody, Ddx5 antibody, DDX5_HUMAN antibody, DEAD (Asp Glu Ala Asp) box helicase 5 antibody, DEAD (Asp Glu Ala Asp) box polypeptide 5 antibody, DEAD box 5 antibody, DEAD box protein 5 antibody, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 5 (RNA helicase, 68kD) antibody, G17P1 antibody, HELR antibody, HLR1 antibody, HUMP68 antibody, P68 antibody, p68 RNA helicase antibody, Probable ATP dependent RNA helicase DDX5 antibody, Probable ATP-dependent RNA helicase DDX5 antibody, RNA helicase p68 antibody

    UniProt

    P17844

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Response to DNA Damage Stimulus
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